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1800–1882 · Organic Chemistry

Friedrich Wöhler

German chemist whose synthesis of urea from inorganic materials challenged vitalism and helped launch organic chemistry.

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Early Life

Born in 1800 in Eschersheim near Frankfurt, Wöhler was the son of a veterinarian and agriculturist. As a boy he collected minerals and performed chemistry experiments at home. He studied medicine at Marburg and Heidelberg, earning a medical degree in 1823, but was persuaded by Leopold Gmelin to pursue chemistry. He then spent a year in Stockholm working under the great Swedish chemist Jöns Jacob Berzelius.

Major Discoveries

  • 01Synthesis of urea from ammonium cyanate (1828)
  • 02Isolated aluminium (1827) and beryllium and yttrium (1828)
  • 03Discovered calcium carbide and derived acetylene from it
  • 04Co-discovered the concept of functional groups (benzoyl radical) with Liebig
  • 05Studied isomerism alongside Liebig's work on fulminates
  • 06Prepared silicon nitride and silane compounds

Famous Experiments

  • 01Heated ammonium cyanate and obtained urea, an organic compound from a living body
  • 02Reduced aluminium chloride with potassium to obtain aluminium metal
  • 03Worked with Liebig on bitter almond oil to identify the benzoyl radical

Awards & Honors

  • 01Copley Medal of the Royal Society (1872)
  • 02Foreign Member of the Royal Society (1854)
  • 03Order Pour le Mérite for Sciences and Arts

Legacy

Wöhler's urea synthesis is seen as the symbolic birth of organic chemistry, showing that life's molecules obey ordinary chemical laws. As a professor in Göttingen for nearly 50 years, he trained thousands of chemists.

Fun Facts

  • 01He wrote to Berzelius: 'I can make urea without the use of kidneys'
  • 02Aluminium was then more precious than gold
  • 03He and Liebig remained lifelong friends despite opposite temperaments
  • 04He translated many of Berzelius's works into German